Aplastic anaemia: a review.
نویسندگان
چکیده
Aplastic anaemia is featured by bone marrow hypocellularity and peripheral pancytopenia and is a potentially fatal disease. In recent years, insight in it pathogenesis has increased. It appears that activated autoreactive T lymphocytes induce apoptosis of haematopoietic stem cells resulting in a hypocellular bone marrow. Nowadays, it can be treated by stem cell transplantation or immunosuppressive therapy. This review focuses on the pathophysiology and treatment of aplastic anaemia.
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ورودعنوان ژورنال:
- The Netherlands journal of medicine
دوره 61 5 شماره
صفحات -
تاریخ انتشار 2003